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Identification of Suppressors of mbk-2/DYRK by Whole-Genome Sequencing

Screening for suppressor mutations is a powerful method to isolate genes that function in a common pathway or process. Because suppressor mutations often do not have phenotypes on their own, cloning of suppressor loci can be challenging. A method combining whole-genome sequencing (WGS) and single nu...

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Detalles Bibliográficos
Autores principales: Wang, Yuemeng, Wang, Jennifer T., Rasoloson, Dominique, Stitzel, Michael L., O’ Connell, Kevin F., Smith, Harold E., Seydoux, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931558/
https://www.ncbi.nlm.nih.gov/pubmed/24347622
http://dx.doi.org/10.1534/g3.113.009126