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Differential Function of Themis CABIT Domains during T Cell Development
Themis (also named Gasp) is a newly identified Grb2-binding protein that is essential for thymocyte positive selection. Despite the possible involvement of Themis in TCR-mediated signal transduction, its function remains unresolved and controversial. Themis contains two functionally uncharacterized...
Autores principales: | Okada, Toshiyuki, Nitta, Takeshi, Kaji, Kentaro, Takashima, Akiko, Oda, Hiroyo, Tamehiro, Norimasa, Goto, Motohito, Okamura, Tadashi, Patrick, Michael S., Suzuki, Harumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931654/ https://www.ncbi.nlm.nih.gov/pubmed/24586531 http://dx.doi.org/10.1371/journal.pone.0089115 |
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