Cargando…

Aryl Hydrocarbon Receptor Downregulates MYCN Expression and Promotes Cell Differentiation of Neuroblastoma

Neuroblastoma (NB) is the most common malignant disease of infancy. MYCN amplification is a prognostic factor for NB and is a sign of highly malignant disease and poor patient prognosis. In this study, we aimed to investigate novel MYCN-related genes and assess how they affect NB cell behavior. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Pei-Yi, Liao, Yung-Feng, Juan, Hsueh-Fen, Huang, Hsuan-Cheng, Wang, Bo-Jeng, Lu, Yen-Lin, Yu, I-Shing, Shih, Yu-Yin, Jeng, Yung-Ming, Hsu, Wen-Ming, Lee, Hsinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931655/
https://www.ncbi.nlm.nih.gov/pubmed/24586395
http://dx.doi.org/10.1371/journal.pone.0088795