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A Compartmentalized Mathematical Model of the β(1)-Adrenergic Signaling System in Mouse Ventricular Myocytes
The β(1)-adrenergic signaling system plays an important role in the functioning of cardiac cells. Experimental data shows that the activation of this system produces inotropy, lusitropy, and chronotropy in the heart, such as increased magnitude and relaxation rates of [Ca(2+)](i) transients and cont...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931689/ https://www.ncbi.nlm.nih.gov/pubmed/24586529 http://dx.doi.org/10.1371/journal.pone.0089113 |