IL-10-Producing B Cells Are Induced Early in HIV-1 Infection and Suppress HIV-1-Specific T Cell Responses

A rare subset of IL-10-producing B cells, named regulatory B cells (Bregs), suppresses adaptive immune responses and inflammation in mice. In this study, we examined the role of IL-10-producing B cells in HIV-1 infection. Compared to uninfected controls, IL-10-producing B cell frequencies were eleva...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Zhan, Wei, Kim, Connie J., Clayton, Kiera, Zhao, Hanqi, Lee, Erika, Cao, Jin Chao, Ziegler, Blake, Gregor, Alexander, Yue, Feng Yun, Huibner, Sanja, MacParland, Sonya, Schwartz, Jordan, Song, Hai Han, Benko, Erika, Gyenes, Gabor, Kovacs, Colin, Kaul, Rupert, Ostrowski, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931714/
https://www.ncbi.nlm.nih.gov/pubmed/24586620
http://dx.doi.org/10.1371/journal.pone.0089236

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