Cargando…

A Core Invasiveness Gene Signature Reflects Epithelial-to-Mesenchymal Transition but Not Metastatic Potential in Breast Cancer Cell Lines and Tissue Samples

INTRODUCTION: Metastases remain the primary cause of cancer-related death. The acquisition of invasive tumour cell behaviour is thought to be a cornerstone of the metastatic cascade. Therefore, gene signatures related to invasiveness could aid in stratifying patients according to their prognostic pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marsan, Melike, Van den Eynden, Gert, Limame, Ridha, Neven, Patrick, Hauspy, Jan, Van Dam, Peter A., Vergote, Ignace, Dirix, Luc Y., Vermeulen, Peter B., Van Laere, Steven J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931724/ https://www.ncbi.nlm.nih.gov/pubmed/24586640 http://dx.doi.org/10.1371/journal.pone.0089262

Ejemplares similares

Dysregulation of microRNAs in breast cancer and their potential role as prognostic and predictive biomarkers in patient management
por: van Schooneveld, Eleni, et al.
Publicado: (2015)

The interaction between ER and NFκB in resistance to endocrine therapy
por: Sas, Leen, et al.
Publicado: (2012)

Expression profiling of cancerous and normal breast tissues identifies microRNAs that are differentially expressed in serum from patients with (metastatic) breast cancer and healthy volunteers
por: van Schooneveld, Eleni, et al.
Publicado: (2012)

Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patients
por: Van der Auwera, Ilse, et al.
Publicado: (2010)

Integrated miRNA and mRNA expression profiling of the inflammatory breast cancer subtype
por: Van der Auwera, I, et al.
Publicado: (2010)

Study Assessing the Quality of Quantification of Estrogen Receptor Protein Expression by Immunohistochemistry and Gene Expression in Breast Cancer
por: Leen, Sas, et al.
Publicado: (2014)

Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast cancer
por: Limame, Ridha, et al.
Publicado: (2013)

Molecular profiles to biology and pathways: a systems biology approach
por: Van Laere, Steven, et al.
Publicado: (2016)

Are Costs of Robot-Assisted Surgery Warranted for Gynecological Procedures?
por: van Dam, Peter, et al.
Publicado: (2011)

Automated enumeration and phenotypic characterization of CTCs and tdEVs in patients with metastatic castration resistant prostate cancer
por: Oeyen, Steffi, et al.
Publicado: (2020)

A dynamic clinical pathway for the treatment of patients with early breast cancer is a tool for better cancer care: implementation and prospective analysis between 2002–2010
por: van Dam, Peter A, et al.
Publicado: (2013)

Circulating tumour cells in the central and the peripheral venous compartment in patients with metastatic breast cancer
por: Peeters, D J E, et al.
Publicado: (2011)

Inflammatory breast carcinoma as a model of accelerated self-metastatic expansion by intravascular growth
por: Vermeulen, P B, et al.
Publicado: (2009)

Detection and prognostic significance of circulating tumour cells in patients with metastatic breast cancer according to immunohistochemical subtypes
por: Peeters, D J E, et al.
Publicado: (2014)

Distinct molecular phenotype of inflammatory breast cancer compared to non-inflammatory breast cancer using Affymetrix-based genome-wide gene-expression analysis
por: Van Laere, S, et al.
Publicado: (2007)

NF-κB activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivation
por: Van Laere, S J, et al.
Publicado: (2007)

Distinguishing blood and lymph vessel invasion in breast cancer: a prospective immunohistochemical study
por: Van den Eynden, G G, et al.
Publicado: (2006)

Induction of lymphangiogenesis in and around axillary lymph node metastases of patients with breast cancer
por: Van den Eynden, G G, et al.
Publicado: (2006)

Circulating tumor cell detection: A prospective comparison between CellSearch® and RareCyte® platforms in patients with progressive metastatic breast cancer
por: Dirix, Luc, et al.
Publicado: (2022)

Benchmarking and audit of breast units improves quality of care
por: van Dam, P.A., et al.
Publicado: (2013)

HER-2 status of circulating tumor cells in a metastatic breast cancer cohort: A comparative study on characterization techniques
por: Brouwer, Anja, et al.
Publicado: (2019)

Angiogenesis and hypoxia in lymph node metastases is predicted by the angiogenesis and hypoxia in the primary tumour in patients with breast cancer
por: Van den Eynden, G G, et al.
Publicado: (2005)

Array-Based DNA Methylation Profiling for Breast Cancer Subtype Discrimination
por: Van der Auwera, Ilse, et al.
Publicado: (2010)

Relative microvessel area of the primary tumour, and not lymph node status, predicts the presence of bone marrow micrometastases detected by reverse transcriptase polymerase chain reaction in patients with clinically non-metastatic breast cancer
por: Benoy, Ina H, et al.
Publicado: (2005)

Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting
por: Peeters, D J E, et al.
Publicado: (2013)

The VEGF pathway and the AKT/mTOR/p70S6K1 signalling pathway in human epithelial ovarian cancer
por: Trinh, X B, et al.
Publicado: (2009)

Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis
por: Mayrhofer, Markus, et al.
Publicado: (2018)

Coagulation/fibrinolysis and circulating tumor cells in patients with advanced breast cancer
por: Dirix, Luc Y., et al.
Publicado: (2022)

Using a Novel Whole Slide Imaging Software Platform for an International Multicenter Validation Study to Assess the Histological Growth Pattern of Liver Metastases
por: Sucaet, Yves, et al.
Publicado: (2014)

Circulating tumour cell detection: a direct comparison between the CellSearch System, the AdnaTest and CK-19/mammaglobin RT–PCR in patients with metastatic breast cancer
por: Van der Auwera, I, et al.
Publicado: (2010)

Aberrant methylation of the Adenomatous Polyposis Coli (APC) gene promoter is associated with the inflammatory breast cancer phenotype
por: Van der Auwera, I, et al.
Publicado: (2008)

Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer
por: Steenbrugge, Jonas, et al.
Publicado: (2019)

Squamous Cell Carcinomas of the Skin Explore Angiogenesis-Independent Mechanisms of Tumour Vascularization
por: Pastushenko, Ievgenia, et al.
Publicado: (2014)

Type IV collagen as a potential biomarker of metastatic breast cancer
por: Lindgren, Moa, et al.
Publicado: (2021)

Real-time RT–PCR correlates with immunocytochemistry for the detection of disseminated epithelial cells in bone marrow aspirates of patients with breast cancer
por: Benoy, I H, et al.
Publicado: (2004)

Microarray-Based Oncogenic Pathway Profiling in Advanced Serous Papillary Ovarian Carcinoma
por: Trinh, Xuan Bich, et al.
Publicado: (2011)

A phase I dose-escalation trial of stereotactic ablative body radiotherapy for non-spine bone and lymph node metastases (DESTROY-trial)
por: Mercier, Carole, et al.
Publicado: (2018)

Comparison of the genomic alterations present in tumor samples from patients with metastatic inflammatory versus non-inflammatory breast cancer reveals AURKA as a potential treatment target
por: Richard, François, et al.
Publicado: (2023)

Evaluation and consequences of heterogeneity in the circulating tumor cell compartment
por: Brouwer, Anja, et al.
Publicado: (2016)

Immune landscape of inflammatory breast cancer suggests vulnerability to immune checkpoint inhibitors
por: Bertucci, François, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bdd7rbt3c0i7snc1q2b73rd85g