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The Antidepressant Trans-2-Phenylcyclopropylamine Protects Mice from High-Fat-Diet-Induced Obesity
Mice treated with the antidepressant trans-2-phenylcyclopropylamine (2-PCPA) were protected against diet-induced-obesity, and adiposity was reversed in pre-established diet-induced obese mice. Contrary to a recent report that inhibition of lysine-specific demethylase-1 by 2-PCPA results in increased...
Autores principales: | Shemesh, Adi, Abdulla, Arian, Yang, Fajun, Chua, Streamson C., Pessin, Jeffrey E., Zong, Haihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931726/ https://www.ncbi.nlm.nih.gov/pubmed/24586592 http://dx.doi.org/10.1371/journal.pone.0089199 |
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