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Discovery of Selective Inhibitors of the Clostridium difficile Dehydroquinate Dehydratase
A vibrant and healthy gut flora is essential for preventing the proliferation of Clostridium difficile, a pathogenic bacterium that causes severe gastrointestinal symptoms. In fact, most C. difficile infections (CDIs) occur after broad-spectrum antibiotic treatment, which, by eradicating the commens...
Autores principales: | Ratia, Kiira, Light, Samuel H., Antanasijevic, Aleksandar, Anderson, Wayne F., Caffrey, Michael, Lavie, Arnon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931744/ https://www.ncbi.nlm.nih.gov/pubmed/24586713 http://dx.doi.org/10.1371/journal.pone.0089356 |
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