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Discovery of Selective Inhibitors of the Clostridium difficile Dehydroquinate Dehydratase

A vibrant and healthy gut flora is essential for preventing the proliferation of Clostridium difficile, a pathogenic bacterium that causes severe gastrointestinal symptoms. In fact, most C. difficile infections (CDIs) occur after broad-spectrum antibiotic treatment, which, by eradicating the commens...

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Detalles Bibliográficos
Autores principales: Ratia, Kiira, Light, Samuel H., Antanasijevic, Aleksandar, Anderson, Wayne F., Caffrey, Michael, Lavie, Arnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931744/
https://www.ncbi.nlm.nih.gov/pubmed/24586713
http://dx.doi.org/10.1371/journal.pone.0089356

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