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Prevalence and Predictors of HIV among Chinese Tuberculosis Patients by Provider-Initiated HIV Testing and Counselling (PITC): A Multisite Study in South Central of China

BACKGROUND: Tuberculosis (TB) and HIV are two worldwide public health concerns. Co-infection of these two diseases has been considered to be a major obstacle for the global efforts in reaching the goals for the prevention of HIV and TB. METHOD: A comprehensive cross-sectional study was conducted to...

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Autores principales: Xu, Junjie, Tang, Weiming, Cheng, Shiming, Mahapatra, Tanmay, Zhou, Lin, Lai, Yuji, Jiang, Yongjun, Liu, Feiying, Zhen, Xinan, He, Jinge, Zhang, Jing, Lu, Jinxin, Mahapatra, Sanchita, Shang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931821/
https://www.ncbi.nlm.nih.gov/pubmed/24586987
http://dx.doi.org/10.1371/journal.pone.0089723
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author Xu, Junjie
Tang, Weiming
Cheng, Shiming
Mahapatra, Tanmay
Zhou, Lin
Lai, Yuji
Jiang, Yongjun
Liu, Feiying
Zhen, Xinan
He, Jinge
Zhang, Jing
Lu, Jinxin
Mahapatra, Sanchita
Shang, Hong
author_facet Xu, Junjie
Tang, Weiming
Cheng, Shiming
Mahapatra, Tanmay
Zhou, Lin
Lai, Yuji
Jiang, Yongjun
Liu, Feiying
Zhen, Xinan
He, Jinge
Zhang, Jing
Lu, Jinxin
Mahapatra, Sanchita
Shang, Hong
author_sort Xu, Junjie
collection PubMed
description BACKGROUND: Tuberculosis (TB) and HIV are two worldwide public health concerns. Co-infection of these two diseases has been considered to be a major obstacle for the global efforts in reaching the goals for the prevention of HIV and TB. METHOD: A comprehensive cross-sectional study was conducted to recruit TB patients in three provinces (Guangxi, Henan and Sichuan) of China between April 1 and September 30, 2010. RESULTS: A total of 1,032 consenting TB patients attended this survey during the study period. Among the participants, 3.30% were HIV positive; about one quarter had opportunistic infections. Nearly half of the participants were 50 years or older, the majority were male and about one third were from minority ethnic groups. After adjusting for site, gender and areas of residence (using the partial/selective Model 1), former commercial plasma donors (adjusted OR [aOR] = 33.71) and injecting drug users(aOR = 15.86) were found to have significantly higher risk of being HIV-positivity. In addition, having extramarital sexual relationship (aOR = 307.16), being engaged in commercial sex (aOR = 252.37), suffering from opportunistic infections in the past six months (aOR = 2.79), losing 10% or more of the body weight in the past six months (aOR = 5.90) and having abnormal chest X-ray findings (aOR = 20.40) were all significantly associated with HIV seropositivity (each p<0.05). CONCLUSIONS: HIV prevalence among TB patients was high in the study areas of China. To control the dual epidemic, intervention strategies targeting socio-demographic and behavioral factors associated with higher risk of TB-HIV co-infection are urgently called for.
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spelling pubmed-39318212014-02-25 Prevalence and Predictors of HIV among Chinese Tuberculosis Patients by Provider-Initiated HIV Testing and Counselling (PITC): A Multisite Study in South Central of China Xu, Junjie Tang, Weiming Cheng, Shiming Mahapatra, Tanmay Zhou, Lin Lai, Yuji Jiang, Yongjun Liu, Feiying Zhen, Xinan He, Jinge Zhang, Jing Lu, Jinxin Mahapatra, Sanchita Shang, Hong PLoS One Research Article BACKGROUND: Tuberculosis (TB) and HIV are two worldwide public health concerns. Co-infection of these two diseases has been considered to be a major obstacle for the global efforts in reaching the goals for the prevention of HIV and TB. METHOD: A comprehensive cross-sectional study was conducted to recruit TB patients in three provinces (Guangxi, Henan and Sichuan) of China between April 1 and September 30, 2010. RESULTS: A total of 1,032 consenting TB patients attended this survey during the study period. Among the participants, 3.30% were HIV positive; about one quarter had opportunistic infections. Nearly half of the participants were 50 years or older, the majority were male and about one third were from minority ethnic groups. After adjusting for site, gender and areas of residence (using the partial/selective Model 1), former commercial plasma donors (adjusted OR [aOR] = 33.71) and injecting drug users(aOR = 15.86) were found to have significantly higher risk of being HIV-positivity. In addition, having extramarital sexual relationship (aOR = 307.16), being engaged in commercial sex (aOR = 252.37), suffering from opportunistic infections in the past six months (aOR = 2.79), losing 10% or more of the body weight in the past six months (aOR = 5.90) and having abnormal chest X-ray findings (aOR = 20.40) were all significantly associated with HIV seropositivity (each p<0.05). CONCLUSIONS: HIV prevalence among TB patients was high in the study areas of China. To control the dual epidemic, intervention strategies targeting socio-demographic and behavioral factors associated with higher risk of TB-HIV co-infection are urgently called for. Public Library of Science 2014-02-21 /pmc/articles/PMC3931821/ /pubmed/24586987 http://dx.doi.org/10.1371/journal.pone.0089723 Text en © 2014 Xu et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Xu, Junjie
Tang, Weiming
Cheng, Shiming
Mahapatra, Tanmay
Zhou, Lin
Lai, Yuji
Jiang, Yongjun
Liu, Feiying
Zhen, Xinan
He, Jinge
Zhang, Jing
Lu, Jinxin
Mahapatra, Sanchita
Shang, Hong
Prevalence and Predictors of HIV among Chinese Tuberculosis Patients by Provider-Initiated HIV Testing and Counselling (PITC): A Multisite Study in South Central of China
title Prevalence and Predictors of HIV among Chinese Tuberculosis Patients by Provider-Initiated HIV Testing and Counselling (PITC): A Multisite Study in South Central of China
title_full Prevalence and Predictors of HIV among Chinese Tuberculosis Patients by Provider-Initiated HIV Testing and Counselling (PITC): A Multisite Study in South Central of China
title_fullStr Prevalence and Predictors of HIV among Chinese Tuberculosis Patients by Provider-Initiated HIV Testing and Counselling (PITC): A Multisite Study in South Central of China
title_full_unstemmed Prevalence and Predictors of HIV among Chinese Tuberculosis Patients by Provider-Initiated HIV Testing and Counselling (PITC): A Multisite Study in South Central of China
title_short Prevalence and Predictors of HIV among Chinese Tuberculosis Patients by Provider-Initiated HIV Testing and Counselling (PITC): A Multisite Study in South Central of China
title_sort prevalence and predictors of hiv among chinese tuberculosis patients by provider-initiated hiv testing and counselling (pitc): a multisite study in south central of china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931821/
https://www.ncbi.nlm.nih.gov/pubmed/24586987
http://dx.doi.org/10.1371/journal.pone.0089723
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