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Association between Vitamin D Status and Risk of Metabolic Syndrome among Korean Postmenopausal Women
This study aimed to investigate the association between serum levels of 25-hydroxyvitamin D [25(OH)D] and metabolic syndrome along with its associated risk factors in Korean postmenopausal women. This study was performed using data from the KNHANES 2008–2010 study and included 4,364 postmenopausal K...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931824/ https://www.ncbi.nlm.nih.gov/pubmed/24586986 http://dx.doi.org/10.1371/journal.pone.0089721 |
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author | Chon, Seung Joo Yun, Bo Hyon Jung, Yeon Soo Cho, Si Hyun Choi, Young Sik Kim, Suk Young Lee, Byung Seok Seo, Seok Kyo |
author_facet | Chon, Seung Joo Yun, Bo Hyon Jung, Yeon Soo Cho, Si Hyun Choi, Young Sik Kim, Suk Young Lee, Byung Seok Seo, Seok Kyo |
author_sort | Chon, Seung Joo |
collection | PubMed |
description | This study aimed to investigate the association between serum levels of 25-hydroxyvitamin D [25(OH)D] and metabolic syndrome along with its associated risk factors in Korean postmenopausal women. This study was performed using data from the KNHANES 2008–2010 study and included 4,364 postmenopausal Korean women. Clinical and other objective characteristics, seasonality, and presence of metabolic syndrome with its five components were evaluated and correlated with the serum levels of 25(OH)D. Although no statistically significant associations were observed between the levels of serum 25(OH)D and the prevalence of metabolic syndrome, the adjusted OR for elevated blood pressure, elevated triglycerides (TGs), and reduced high-density lipoprotein cholesterol (HDL-C) showed tendency to decrease sequentially as tertiles of serum 25(OH)D levels increased (p for trends = 0.066, 0.043, and 0.010, respectively). Women in the highest tertile of serum 25(OH)D showed a significant decrease in the prevalence of elevated blood pressure, elevated TGs, and reduced HDL-C as compared with those in the lowest tertile of serum 25(OH)D (p = 0.020, 0.014, and 0.002, respectively). Based on these results, we consider that adequate serum levels of 25(OH)D in Korean postmenopausal women may not entirely indicate a lower risk of developing metabolic syndrome. However, adequate serum levels of 25(OH)D are significantly associated with a decrease in elevated blood pressure, elevated TGs, and reduced HDL-C levels in postmenopausal women. |
format | Online Article Text |
id | pubmed-3931824 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-39318242014-02-25 Association between Vitamin D Status and Risk of Metabolic Syndrome among Korean Postmenopausal Women Chon, Seung Joo Yun, Bo Hyon Jung, Yeon Soo Cho, Si Hyun Choi, Young Sik Kim, Suk Young Lee, Byung Seok Seo, Seok Kyo PLoS One Research Article This study aimed to investigate the association between serum levels of 25-hydroxyvitamin D [25(OH)D] and metabolic syndrome along with its associated risk factors in Korean postmenopausal women. This study was performed using data from the KNHANES 2008–2010 study and included 4,364 postmenopausal Korean women. Clinical and other objective characteristics, seasonality, and presence of metabolic syndrome with its five components were evaluated and correlated with the serum levels of 25(OH)D. Although no statistically significant associations were observed between the levels of serum 25(OH)D and the prevalence of metabolic syndrome, the adjusted OR for elevated blood pressure, elevated triglycerides (TGs), and reduced high-density lipoprotein cholesterol (HDL-C) showed tendency to decrease sequentially as tertiles of serum 25(OH)D levels increased (p for trends = 0.066, 0.043, and 0.010, respectively). Women in the highest tertile of serum 25(OH)D showed a significant decrease in the prevalence of elevated blood pressure, elevated TGs, and reduced HDL-C as compared with those in the lowest tertile of serum 25(OH)D (p = 0.020, 0.014, and 0.002, respectively). Based on these results, we consider that adequate serum levels of 25(OH)D in Korean postmenopausal women may not entirely indicate a lower risk of developing metabolic syndrome. However, adequate serum levels of 25(OH)D are significantly associated with a decrease in elevated blood pressure, elevated TGs, and reduced HDL-C levels in postmenopausal women. Public Library of Science 2014-02-21 /pmc/articles/PMC3931824/ /pubmed/24586986 http://dx.doi.org/10.1371/journal.pone.0089721 Text en © 2014 Chon et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Chon, Seung Joo Yun, Bo Hyon Jung, Yeon Soo Cho, Si Hyun Choi, Young Sik Kim, Suk Young Lee, Byung Seok Seo, Seok Kyo Association between Vitamin D Status and Risk of Metabolic Syndrome among Korean Postmenopausal Women |
title | Association between Vitamin D Status and Risk of Metabolic Syndrome among Korean Postmenopausal Women |
title_full | Association between Vitamin D Status and Risk of Metabolic Syndrome among Korean Postmenopausal Women |
title_fullStr | Association between Vitamin D Status and Risk of Metabolic Syndrome among Korean Postmenopausal Women |
title_full_unstemmed | Association between Vitamin D Status and Risk of Metabolic Syndrome among Korean Postmenopausal Women |
title_short | Association between Vitamin D Status and Risk of Metabolic Syndrome among Korean Postmenopausal Women |
title_sort | association between vitamin d status and risk of metabolic syndrome among korean postmenopausal women |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931824/ https://www.ncbi.nlm.nih.gov/pubmed/24586986 http://dx.doi.org/10.1371/journal.pone.0089721 |
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