Cargando…

Eugenol triggers apoptosis in breast cancer cells through E2F1/survivin down-regulation

BACKGROUND: Breast cancer is a major health problem that threatens the lives of millions of women worldwide each year. Most of the chemotherapeutic agents that are currently used to treat this complex disease are highly toxic with long-term side effects. Therefore, novel generation of anti-cancer dr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al-Sharif, Ibtehaj, Remmal, Adnane, Aboussekhra, Abdelilah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931838/ https://www.ncbi.nlm.nih.gov/pubmed/24330704 http://dx.doi.org/10.1186/1471-2407-13-600

Ejemplares similares

Sequential combination of cisplatin with eugenol targets ovarian cancer stem cells through the Notch-Hes1 signalling pathway
por: Islam, Syed S., et al.
Publicado: (2019)

Preserving Soybean Oil for the Frying of Breaded Butterfly Shrimp Using Natural Rosemary Antioxidant
por: Moufakkir, Chaimae, et al.
Publicado: (2023)

ATR suppresses the pro-tumorigenic functions of breast stromal fibroblasts
por: Al-Ansari, Mysoon M., et al.
Publicado: (2018)

CHEK2 represses breast stromal fibroblasts and their paracrine tumor-promoting effects through suppressing SDF-1 and IL-6
por: Al-Rakan, Maha A., et al.
Publicado: (2016)

Osteoprotegerin (OPG) Upregulation Activates Breast Stromal Fibroblasts and Enhances Their Pro-Carcinogenic Effects through the STAT3/IL-6 Signaling
por: Al-Nasrallah, Huda K., et al.
Publicado: (2022)

Let-7b inhibits cancer-promoting effects of breast cancer-associated fibroblasts through IL-8 repression
por: Al-Harbi, Bothina, et al.
Publicado: (2018)

Caffeine Mediates Sustained Inactivation of Breast Cancer-Associated Myofibroblasts via Up-Regulation of Tumor Suppressor Genes
por: Al-Ansari, Mysoon M., et al.
Publicado: (2014)

AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma
por: Al-Khalaf, Huda H., et al.
Publicado: (2019)

miR-146b-5p mediates p16-dependent repression of IL-6 and suppresses paracrine procarcinogenic effects of breast stromal fibroblasts
por: Al-Ansari, Mysoon M., et al.
Publicado: (2015)

PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells
por: Al-Howail, Huda A., et al.
Publicado: (2016)

p16(INK4A) Positively Regulates Cyclin D1 and E2F1 through Negative Control of AUF1
por: Al-Khalaf, Huda H., et al.
Publicado: (2011)

Down-Regulation of Survivin by Nemadipine-A Sensitizes Cancer Cells to TRAIL-Induced Apoptosis
por: Park, Seong Ho, et al.
Publicado: (2013)

Up-regulation of 5-lipoxygenase by inhibition of cathepsin G enhances TRAIL-induced apoptosis through down-regulation of survivin
por: Woo, Seon Min, et al.
Publicado: (2017)

Activated breast stromal fibroblasts exhibit myoepithelial and mammary stem cells features
por: Aboussekhra, Abdelilah, et al.
Publicado: (2023)

Co-Delivery of Eugenol and Dacarbazine by Hyaluronic Acid-Coated Liposomes for Targeted Inhibition of Survivin in Treatment of Resistant Metastatic Melanoma
por: Mishra, Harshita, et al.
Publicado: (2019)

Eugenol triggers CD11b(+)Gr1(+) myeloid-derived suppressor cell apoptosis via endogenous apoptosis pathway
por: Ding, Ying, et al.
Publicado: (2018)

p16(INK4A) Positively Regulates p21(WAF1) Expression by suppressing AUF1-dependent mRNA decay
por: Al-Khalaf, Huda H., et al.
Publicado: (2013)

The DNA methyl-transferase protein DNMT1 enhances tumor-promoting properties of breast stromal fibroblasts
por: Al-Kharashi, Layla A., et al.
Publicado: (2017)

Acid-Triggered Release of Eugenol and Fluoride by Desensitizing Macro- and Nanoparticles
por: Sereda, Grigoriy, et al.
Publicado: (2023)

Ionizing radiation normalizes the features of active breast cancer stromal fibroblasts and suppresses their paracrine pro-carcinogenic effects
por: Aboussekhra, Abdelilah, et al.
Publicado: (2023)

Adsorption of Polyphenols from Almond Blanching Water by Macroporous Resin
por: Tabib, Malak, et al.
Publicado: (2022)

In Vitro and In Vivo Comparison of Changes in Antibiotics Susceptibility of E. coli and Chicken's Intestinal Flora after Exposure to Amoxicillin or Thymol
por: Hriouech, Soukayna, et al.
Publicado: (2020)

Modulation Effects of Eugenol on Nephrotoxicity Triggered by Silver Nanoparticles in Adult Rats
por: Aboelwafa, Hanaa R., et al.
Publicado: (2022)

Antiproliferative and Molecular Mechanism of Eugenol-Induced Apoptosis in Cancer Cells
por: Jaganathan, Saravana Kumar, et al.
Publicado: (2012)

Obesity is a significant risk factor for breast cancer in Arab women
por: Elkum, Naser, et al.
Publicado: (2014)

HEPATOTOXICITY OF EUGENOL
por: Soundran, Vijaya, et al.
Publicado: (1994)

Tea polyphenols induced apoptosis of breast cancer cells by suppressing the expression of Survivin
por: Chen, Xuesong, et al.
Publicado: (2014)

The inflammatory/cancer-related IL-6/STAT3/NF-κB positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts
por: Hendrayani, Siti-Fauziah, et al.
Publicado: (2016)

Expression of survivin and its splice variants survivin-2B and survivin-ΔEx3 in breast cancer
por: Ryan, B, et al.
Publicado: (2005)

Discovery of Novel 3-Cyanopyridines as Survivin Modulators and Apoptosis Inducers
por: Sabour, Rehab, et al.
Publicado: (2020)

An otoprotective role for the apoptosis inhibitor protein survivin
por: Knauer, S K, et al.
Publicado: (2010)

AUF1 promotes stemness in human mammary epithelial cells through stabilization of the EMT transcription factors TWIST1 and SNAIL1
por: AlAhmari, Manar M., et al.
Publicado: (2020)

High DNMT1 Expression in Stromal Fibroblasts Promotes Angiogenesis and Unfavorable Outcome in Locally Advanced Breast Cancer Patients
por: Al-Kharashi, Layla A., et al.
Publicado: (2022)

High AUF1 level in stromal fibroblasts promotes carcinogenesis and chemoresistance and predicts unfavorable prognosis among locally advanced breast cancer patients
por: Al-Tweigeri, Taher, et al.
Publicado: (2022)

Eugenol alleviated breast precancerous lesions through HER2/PI3K-AKT pathway-induced cell apoptosis and S-phase arrest
por: Ma, Min, et al.
Publicado: (2017)

Synthesis of Isomers of Eugenol
por: Brauer, Gerhard M., et al.
Publicado: (1963)

Eugenol-Induced Autophagy and Apoptosis in Breast Cancer Cells via PI3K/AKT/FOXO3a Pathway Inhibition
por: Abdullah, Mashan L., et al.
Publicado: (2021)

Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives
por: Makuch, Edyta, et al.
Publicado: (2020)

The Antistaphylococcal Activity of Amoxicillin/Clavulanic Acid, Gentamicin, and 1,8-Cineole Alone or in Combination and Their Efficacy through a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Osteomyelitis
por: Hriouech, Soukayna, et al.
Publicado: (2020)

Cellular apoptosis and cell cycle arrest as potential therapeutic targets for eugenol derivatives in Candida auris
por: Alam, Hammad, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5sbeibru600mqivarvdc2l2hoh