Comparison of Reverse Transcription Quantitative Real-Time PCR, Flow Cytometry, and Immunohistochemistry for Detection of Monoclonality in Lymphomas

In healthy humans, 60–70% of the B lymphocytes produce kappa light chains, while the remaining cells produce lambda light chains. Malignant transformation and clonal expansion of B lymphocytes lead to an altered kappa : lambda expression ratio, which is an important diagnostic criteria of lymphomas....

Descripción completa

Detalles Bibliográficos
Autores principales: Ståhlberg, Anders, Åman, Pierre, Strömbom, Linda, Zoric, Neven, Diez, Alfredo, Nilsson, Olle, Kubista, Mikael, Ridell, Börje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932212/
https://www.ncbi.nlm.nih.gov/pubmed/24649374
http://dx.doi.org/10.1155/2014/796210

Ejemplares similares

Ejemplares similares