Cargando…

Glucagon-Like Peptide-1 Secreting Cell Function as well as Production of Inflammatory Reactive Oxygen Species Is Differently Regulated by Glycated Serum and High Levels of Glucose

Glucagon-like peptide-1 (GLP-1), an intestinal hormone contributing to glucose homeostasis, is synthesized by proglucagon and secreted from intestinal neuroendocrine cells in response to nutrients. GLP-1 secretion is impaired in type 2 diabetes patients. Here, we aimed at investigating whether diabe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Puddu, Alessandra, Sanguineti, Roberta, Montecucco, Fabrizio, Viviani, Giorgio L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932225/ https://www.ncbi.nlm.nih.gov/pubmed/24648662 http://dx.doi.org/10.1155/2014/923120

Ejemplares similares

Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum
por: Puddu, Alessandra, et al.
Publicado: (2013)

Effects of High Glucose Levels and Glycated Serum on GIP Responsiveness in the Pancreatic Beta Cell Line HIT-T15
por: Puddu, Alessandra, et al.
Publicado: (2015)

Retinal Pigment Epithelial Cells Express a Functional Receptor for Glucagon-Like Peptide-1 (GLP-1)
por: Puddu, Alessandra, et al.
Publicado: (2013)

An Emerging Role of Glucagon-Like Peptide-1 in Preventing Advanced-Glycation-End-Product-Mediated Damages in Diabetes
por: Puddu, Alessandra, et al.
Publicado: (2013)

Advanced Glycation End Products Play Adverse Proinflammatory Activities in Osteoporosis
por: Sanguineti, Roberta, et al.
Publicado: (2014)

Vascular endothelial growth factor-C secretion is increased by advanced glycation end-products: possible implication in ocular neovascularization
por: Puddu, Alessandra, et al.
Publicado: (2012)

Evidence for the Gut Microbiota Short-Chain Fatty Acids as Key Pathophysiological Molecules Improving Diabetes
por: Puddu, Alessandra, et al.
Publicado: (2014)

Update on the Protective Molecular Pathways Improving Pancreatic Beta-Cell Dysfunction
por: Puddu, Alessandra, et al.
Publicado: (2013)

miR-126 Mimic Counteracts the Increased Secretion of VEGF-A Induced by High Glucose in ARPE-19 Cells
por: Sanguineti, Roberta, et al.
Publicado: (2021)

Advanced Glycation End-Products and Hyperglycemia Increase Angiopoietin-2 Production by Impairing Angiopoietin-1-Tie-2 System
por: Puddu, Alessandra, et al.
Publicado: (2019)

Caveolin-1 Down-Regulation Reduces VEGF-A Secretion Induced by IGF-1 in ARPE-19 Cells
por: Puddu, Alessandra, et al.
Publicado: (2021)

Mechanisms underlying glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1 secretion
por: Reimann, Frank, et al.
Publicado: (2016)

Carbohydrate‐induced secretion of glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1
por: Seino, Yusuke, et al.
Publicado: (2016)

Glucagon‐like peptide‐1 and glucose‐dependent insulinotropic peptide: effects alone and in combination on insulin secretion and glucose disappearance in mice
por: Pacini, Giovanni, et al.
Publicado: (2017)

Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion
por: Parker, H. E., et al.
Publicado: (2012)

Glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1 secretion in humans: Characteristics and regulation
por: Alsalim, Wathik, et al.
Publicado: (2022)

Glucagon-like peptide-1 receptor blockade impairs islet secretion and glucose metabolism in humans
por: Welch, Andrew A., et al.
Publicado: (2023)

Sodium, Glucose and Dysregulated Glucagon Secretion: The Potential of Sodium Glucose Transporters
por: Armour, Sarah L., et al.
Publicado: (2022)

Impaired Secretion of Total Glucagon-like Peptide-1 in People with Impaired Fasting Glucose Combined Impaired Glucose Tolerance
por: Zhang, Fang, et al.
Publicado: (2012)

Glucagon-Like Peptide-1 Receptor Agonist and Glucagon Increase Glucose-Stimulated Insulin Secretion in Beta Cells via Distinct Adenylyl Cyclases
por: Lee, Young-Sun, et al.
Publicado: (2018)

Ingestion of Diet Soda Before a Glucose Load Augments Glucagon-Like Peptide-1 Secretion
por: Brown, Rebecca J., et al.
Publicado: (2009)

Intra-islet glucagon secretion and action in the regulation of glucose homeostasis
por: Wang, Qinghua, et al.
Publicado: (2013)

α-cell glucokinase suppresses glucose-regulated glucagon secretion
por: Basco, Davide, et al.
Publicado: (2018)

γ-Hydroxybutyrate does not mediate glucose inhibition of glucagon secretion
por: Yu, Qian, et al.
Publicado: (2020)

Multiple Factors Related to the Secretion of Glucagon-Like Peptide-1
por: Wang, XingChun, et al.
Publicado: (2015)

Glucagon-like Peptide-1 Secretion Is Inhibited by Lysophosphatidic Acid
por: Fernandes, Maria F., et al.
Publicado: (2022)

Glucose-Induced Glucagon-Like Peptide 1 Secretion Is Deficient in Patients with Non-Alcoholic Fatty Liver Disease
por: Bernsmeier, Christine, et al.
Publicado: (2014)

Mathematical Modeling of Interacting Glucose-Sensing Mechanisms and Electrical Activity Underlying Glucagon-Like Peptide 1 Secretion
por: Riz, Michela, et al.
Publicado: (2015)

Glucose Control of Glucagon Secretion: There Is More to It Than K(ATP) Channels
por: Gylfe, Erik
Publicado: (2013)

Subthreshold α (2)-Adrenergic Activation Counteracts Glucagon-Like Peptide-1 Potentiation of Glucose-Stimulated Insulin Secretion
por: Pan, Minglin, et al.
Publicado: (2011)

Effect of targeted estrogen delivery using glucagon-like peptide-1 on insulin secretion, insulin sensitivity and glucose homeostasis
por: Tiano, Joseph P., et al.
Publicado: (2015)

β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion
por: Robson-Doucette, Christine A., et al.
Publicado: (2011)

Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion
por: Leloup, Corinne, et al.
Publicado: (2009)

Chicken Intestinal L Cells and Glucagon-like Peptide-1 Secretion
por: Hiramatsu, Kohzy
Publicado: (2020)

Glucose controls glucagon secretion by directly modulating cAMP in alpha cells
por: Yu, Qian, et al.
Publicado: (2019)

Glucose, adrenaline and palmitate antagonistically regulate insulin and glucagon secretion in human pseudoislets
por: Lorza-Gil, Estela, et al.
Publicado: (2019)

Glucokinase intrinsically regulates glucose sensing and glucagon secretion in pancreatic alpha cells
por: Moede, Tilo, et al.
Publicado: (2020)

Erratum to “Subthreshold α (2)-Adrenergic Activation Counteracts Glucagon-Like Peptide-1 Potentiation of Glucose-Stimulated Insulin Secretion”
por: Pan, Minglin, et al.
Publicado: (2011)

Transient Receptor Potential Vanilloid 1 Activation Enhances Gut Glucagon-Like Peptide-1 Secretion and Improves Glucose Homeostasis
por: Wang, Peijian, et al.
Publicado: (2012)

Delphinidin 3‐rutinoside‐rich blackcurrant extract ameliorates glucose tolerance by increasing the release of glucagon‐like peptide‐1 secretion
por: Tani, Tsubasa, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_dcc6rfoungpna4hk55dcptuk0o