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DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12
Two genetic findings from twin research have far-reaching implications for understanding individual differences in the development of brain function as indexed by general cognitive ability (g, aka intelligence): (1) The same genes affect g throughout development, even though (2) heritability increas...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932402/ https://www.ncbi.nlm.nih.gov/pubmed/23358157 http://dx.doi.org/10.1038/mp.2012.191 |
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author | Trzaskowski, M Yang, J Visscher, P M Plomin, R |
author_facet | Trzaskowski, M Yang, J Visscher, P M Plomin, R |
author_sort | Trzaskowski, M |
collection | PubMed |
description | Two genetic findings from twin research have far-reaching implications for understanding individual differences in the development of brain function as indexed by general cognitive ability (g, aka intelligence): (1) The same genes affect g throughout development, even though (2) heritability increases. It is now possible to test these hypotheses using DNA alone. From 1.7 million DNA markers and g scores at ages 7 and 12 on 2875 children, the DNA genetic correlation from age 7 to 12 was 0.73, highly similar to the genetic correlation of 0.75 estimated from 6702 pairs of twins from the same sample. DNA-estimated heritabilities increased from 0.26 at age 7 to 0.45 at age 12; twin-estimated heritabilities also increased from 0.35 to 0.48. These DNA results confirm the results of twin studies indicating strong genetic stability but increasing heritability for g, despite mean changes in brain structure and function from childhood to adolescence. |
format | Online Article Text |
id | pubmed-3932402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-39324022014-02-24 DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12 Trzaskowski, M Yang, J Visscher, P M Plomin, R Mol Psychiatry Original Article Two genetic findings from twin research have far-reaching implications for understanding individual differences in the development of brain function as indexed by general cognitive ability (g, aka intelligence): (1) The same genes affect g throughout development, even though (2) heritability increases. It is now possible to test these hypotheses using DNA alone. From 1.7 million DNA markers and g scores at ages 7 and 12 on 2875 children, the DNA genetic correlation from age 7 to 12 was 0.73, highly similar to the genetic correlation of 0.75 estimated from 6702 pairs of twins from the same sample. DNA-estimated heritabilities increased from 0.26 at age 7 to 0.45 at age 12; twin-estimated heritabilities also increased from 0.35 to 0.48. These DNA results confirm the results of twin studies indicating strong genetic stability but increasing heritability for g, despite mean changes in brain structure and function from childhood to adolescence. Nature Publishing Group 2014-03 2013-01-29 /pmc/articles/PMC3932402/ /pubmed/23358157 http://dx.doi.org/10.1038/mp.2012.191 Text en Copyright © 2014 Macmillan Publishers Limited http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/ |
spellingShingle | Original Article Trzaskowski, M Yang, J Visscher, P M Plomin, R DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12 |
title | DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12 |
title_full | DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12 |
title_fullStr | DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12 |
title_full_unstemmed | DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12 |
title_short | DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12 |
title_sort | dna evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12 |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932402/ https://www.ncbi.nlm.nih.gov/pubmed/23358157 http://dx.doi.org/10.1038/mp.2012.191 |
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