A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

Blood-brain barrier (BBB) models are often used to investigate BBB function and screen brain-penetrating therapeutics, but it has been difficult to construct a human model that possesses an optimal BBB phenotype and is readily scalable. To address this challenge, we developed a human in vitro BBB mo...

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Detalles Bibliográficos
Autores principales: Lippmann, Ethan S., Al-Ahmad, Abraham, Azarin, Samira M., Palecek, Sean P., Shusta, Eric V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932448/
https://www.ncbi.nlm.nih.gov/pubmed/24561821
http://dx.doi.org/10.1038/srep04160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932448/
https://www.ncbi.nlm.nih.gov/pubmed/24561821
http://dx.doi.org/10.1038/srep04160

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