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Harvest: an open platform for developing web-based biomedical data discovery and reporting applications

Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems that efficiently show relationships between indivi...

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Detalles Bibliográficos
Autores principales: Pennington, Jeffrey W, Ruth, Byron, Italia, Michael J, Miller, Jeffrey, Wrazien, Stacey, Loutrel, Jennifer G, Crenshaw, E Bryan, White, Peter S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932456/
https://www.ncbi.nlm.nih.gov/pubmed/24131510
http://dx.doi.org/10.1136/amiajnl-2013-001825
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author Pennington, Jeffrey W
Ruth, Byron
Italia, Michael J
Miller, Jeffrey
Wrazien, Stacey
Loutrel, Jennifer G
Crenshaw, E Bryan
White, Peter S
author_facet Pennington, Jeffrey W
Ruth, Byron
Italia, Michael J
Miller, Jeffrey
Wrazien, Stacey
Loutrel, Jennifer G
Crenshaw, E Bryan
White, Peter S
author_sort Pennington, Jeffrey W
collection PubMed
description Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems that efficiently show relationships between individual variables, but without the need to navigate underlying data models. We have addressed this need by developing Harvest, an open-source framework of modular components, and using it for the rapid development and deployment of custom data discovery software applications. Harvest incorporates visualizations of highly dimensional data in a web-based interface that promotes rapid exploration and export of any type of biomedical information, without exposing researchers to underlying data models. We evaluated Harvest with two cases: clinical data from pediatric cardiology and demonstration data from the OpenMRS project. Harvest's architecture and public open-source code offer a set of rapid application development tools to build data discovery applications for domain-specific biomedical data repositories. All resources, including the OpenMRS demonstration, can be found at http://harvest.research.chop.edu
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spelling pubmed-39324562014-02-24 Harvest: an open platform for developing web-based biomedical data discovery and reporting applications Pennington, Jeffrey W Ruth, Byron Italia, Michael J Miller, Jeffrey Wrazien, Stacey Loutrel, Jennifer G Crenshaw, E Bryan White, Peter S J Am Med Inform Assoc Case Report Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems that efficiently show relationships between individual variables, but without the need to navigate underlying data models. We have addressed this need by developing Harvest, an open-source framework of modular components, and using it for the rapid development and deployment of custom data discovery software applications. Harvest incorporates visualizations of highly dimensional data in a web-based interface that promotes rapid exploration and export of any type of biomedical information, without exposing researchers to underlying data models. We evaluated Harvest with two cases: clinical data from pediatric cardiology and demonstration data from the OpenMRS project. Harvest's architecture and public open-source code offer a set of rapid application development tools to build data discovery applications for domain-specific biomedical data repositories. All resources, including the OpenMRS demonstration, can be found at http://harvest.research.chop.edu BMJ Publishing Group 2014-03 2013-10-16 /pmc/articles/PMC3932456/ /pubmed/24131510 http://dx.doi.org/10.1136/amiajnl-2013-001825 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Case Report
Pennington, Jeffrey W
Ruth, Byron
Italia, Michael J
Miller, Jeffrey
Wrazien, Stacey
Loutrel, Jennifer G
Crenshaw, E Bryan
White, Peter S
Harvest: an open platform for developing web-based biomedical data discovery and reporting applications
title Harvest: an open platform for developing web-based biomedical data discovery and reporting applications
title_full Harvest: an open platform for developing web-based biomedical data discovery and reporting applications
title_fullStr Harvest: an open platform for developing web-based biomedical data discovery and reporting applications
title_full_unstemmed Harvest: an open platform for developing web-based biomedical data discovery and reporting applications
title_short Harvest: an open platform for developing web-based biomedical data discovery and reporting applications
title_sort harvest: an open platform for developing web-based biomedical data discovery and reporting applications
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932456/
https://www.ncbi.nlm.nih.gov/pubmed/24131510
http://dx.doi.org/10.1136/amiajnl-2013-001825
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