Association of Over-Expressed Estrogen Receptor Alpha with Development of Tamoxifen Resistant Hyperplasia and Adenocarcinomas in Genetically Engineered Mice

BACKGROUND: Estrogen receptor alpha (ERα) and cyclin D1 are frequently co-expressed in human breast cancer. Some, but not all, studies link tamoxifen resistance to co-expression of cyclin D1 and ERα. In mice over-expression of either cyclin D1 or ERα in mammary epithelial cells is sufficient to indu...

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Detalles Bibliográficos
Autores principales: Miermont, Anne M, Cabrera, Marina Carla, Frech, Silvina M, Nakles, Rebecca E, Diaz-Cruz, Edgar S., Shiffert, Maddalena Tilli, Furth, Priscilla A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932557/
https://www.ncbi.nlm.nih.gov/pubmed/24575359

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