Primary mediastinal seminoma; resistance and relapse: An aggressive entity

Seminoma is one of the most radio and chemo sensitive tumors. Aggressive variant of primary mediastinal seminoma (PMS) are rarely described in the literature. We here discuss an interesting case of young male (22 years) presenting with superior vena cava syndrome due to PMS that showed poor response...

Descripción completa

Detalles Bibliográficos
Autores principales: Nachankar, Ankita, Krishnatry, Rahul, Joshi, Amit, Noronha, Vanita, Agarwal, Jai Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932601/
https://www.ncbi.nlm.nih.gov/pubmed/24604963
http://dx.doi.org/10.4103/0971-5851.125252
Descripción
Sumario:Seminoma is one of the most radio and chemo sensitive tumors. Aggressive variant of primary mediastinal seminoma (PMS) are rarely described in the literature. We here discuss an interesting case of young male (22 years) presenting with superior vena cava syndrome due to PMS that showed poor response to conventional platinum based chemotherapy and radiotherapy. Furthermore, with a short disease free interval (one year) relapsed at unusual sites of bone and soft-tissue deposits in check. This emphasizes the importance of identifying methods to pre-screen such aggressive variants for more effective treatment options.

Ejemplares similares