Primary mediastinal seminoma; resistance and relapse: An aggressive entity

Seminoma is one of the most radio and chemo sensitive tumors. Aggressive variant of primary mediastinal seminoma (PMS) are rarely described in the literature. We here discuss an interesting case of young male (22 years) presenting with superior vena cava syndrome due to PMS that showed poor response...

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Autores principales: Nachankar, Ankita, Krishnatry, Rahul, Joshi, Amit, Noronha, Vanita, Agarwal, Jai Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932601/
https://www.ncbi.nlm.nih.gov/pubmed/24604963
http://dx.doi.org/10.4103/0971-5851.125252
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author Nachankar, Ankita
Krishnatry, Rahul
Joshi, Amit
Noronha, Vanita
Agarwal, Jai Prakash
author_facet Nachankar, Ankita
Krishnatry, Rahul
Joshi, Amit
Noronha, Vanita
Agarwal, Jai Prakash
author_sort Nachankar, Ankita
collection PubMed
description Seminoma is one of the most radio and chemo sensitive tumors. Aggressive variant of primary mediastinal seminoma (PMS) are rarely described in the literature. We here discuss an interesting case of young male (22 years) presenting with superior vena cava syndrome due to PMS that showed poor response to conventional platinum based chemotherapy and radiotherapy. Furthermore, with a short disease free interval (one year) relapsed at unusual sites of bone and soft-tissue deposits in check. This emphasizes the importance of identifying methods to pre-screen such aggressive variants for more effective treatment options.
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spelling pubmed-39326012014-03-06 Primary mediastinal seminoma; resistance and relapse: An aggressive entity Nachankar, Ankita Krishnatry, Rahul Joshi, Amit Noronha, Vanita Agarwal, Jai Prakash Indian J Med Paediatr Oncol Case Report Seminoma is one of the most radio and chemo sensitive tumors. Aggressive variant of primary mediastinal seminoma (PMS) are rarely described in the literature. We here discuss an interesting case of young male (22 years) presenting with superior vena cava syndrome due to PMS that showed poor response to conventional platinum based chemotherapy and radiotherapy. Furthermore, with a short disease free interval (one year) relapsed at unusual sites of bone and soft-tissue deposits in check. This emphasizes the importance of identifying methods to pre-screen such aggressive variants for more effective treatment options. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3932601/ /pubmed/24604963 http://dx.doi.org/10.4103/0971-5851.125252 Text en Copyright: © Indian Journal of Medical and Paediatric Oncology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nachankar, Ankita
Krishnatry, Rahul
Joshi, Amit
Noronha, Vanita
Agarwal, Jai Prakash
Primary mediastinal seminoma; resistance and relapse: An aggressive entity
title Primary mediastinal seminoma; resistance and relapse: An aggressive entity
title_full Primary mediastinal seminoma; resistance and relapse: An aggressive entity
title_fullStr Primary mediastinal seminoma; resistance and relapse: An aggressive entity
title_full_unstemmed Primary mediastinal seminoma; resistance and relapse: An aggressive entity
title_short Primary mediastinal seminoma; resistance and relapse: An aggressive entity
title_sort primary mediastinal seminoma; resistance and relapse: an aggressive entity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932601/
https://www.ncbi.nlm.nih.gov/pubmed/24604963
http://dx.doi.org/10.4103/0971-5851.125252
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