Bacteriophages use an expanded genetic code on evolutionary paths to higher fitness

Bioengineering advances have made it possible to fundamentally alter the genetic codes of organisms. However, the evolutionary consequences of expanding an organism's genetic code with a non-canonical amino acid are poorly understood. Here we show that bacteriophages evolved on a host that inco...

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Detalles Bibliográficos
Autores principales: Hammerling, Michael J., Ellefson, Jared W., Boutz, Daniel R., Marcotte, Edward M., Ellington, Andrew D., Barrick, Jeffrey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932624/
https://www.ncbi.nlm.nih.gov/pubmed/24487692
http://dx.doi.org/10.1038/nchembio.1450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932624/
https://www.ncbi.nlm.nih.gov/pubmed/24487692
http://dx.doi.org/10.1038/nchembio.1450

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