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A step closer toward therapies for p63-related disorders

Small molecules with low molecular weight are of interest for drug development, as they are more likely to be absorbed. In cancer research, p53 is often mutated in many tumors, and many small molecules targeting mutant p53 have been tested. One of such low molecular weight compounds is APR246/PRIMA-...

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Detalles Bibliográficos
Autores principales: Zhou, Huiqing, Aberdam, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932939/
https://www.ncbi.nlm.nih.gov/pubmed/25002990
http://dx.doi.org/10.4161/rdis.24247

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