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Engrailed2 modulates cerebellar granule neuron precursor proliferation, differentiation and insulin-like growth factor 1 signaling during postnatal development

BACKGROUND: The homeobox transcription factor Engrailed2 (En2) has been studied extensively in neurodevelopment, particularly in the midbrain/hindbrain region and cerebellum, where it exhibits dynamic patterns of expression and regulates cell patterning and morphogenesis. Because of its roles in reg...

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Detalles Bibliográficos
Autores principales: Rossman, Ian T, Lin, Lulu, Morgan, Katherine M, DiGiovine, Marissa, Van Buskirk, Elise K, Kamdar, Silky, Millonig, James H, DiCicco-Bloom, Emanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932947/
https://www.ncbi.nlm.nih.gov/pubmed/24507165
http://dx.doi.org/10.1186/2040-2392-5-9