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Increased ectodomain shedding of lung epithelial cell adhesion molecule 1 as a cause of increased alveolar cell apoptosis in emphysema

RATIONALE: Alveolar epithelial cell apoptosis and protease/antiprotease imbalance based proteolysis play central roles in the pathogenesis of pulmonary emphysema but molecular mechanisms underlying these two events are not yet clearly understood. Cell adhesion molecule 1 (CADM1) is a lung epithelial...

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Detalles Bibliográficos
Autores principales:	Mimae, Takahiro, Hagiyama, Man, Inoue, Takao, Yoneshige, Azusa, Kato, Takashi, Okada, Morihito, Murakami, Yoshinori, Ito, Akihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2014
Materias:	Chronic Obstructive Pulmonary Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933066/ https://www.ncbi.nlm.nih.gov/pubmed/24092566 http://dx.doi.org/10.1136/thoraxjnl-2013-203867

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