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Immunohistochemical evaluation of phosphorylated SMAD2/SMAD3 and the co-activator P300 in human glomerulonephritis: correlation with renal injury

Background: Smad2 and Smad3 are transcription factors that mediate transforming growth factor beta (TGF-β) signals. Upon their activation, phosphorylated Smad2/Smad3 (pSmad2/Smad3), translocate to the nucleus and associate with co-activators such as p300, regulating the transcription of genes that c...

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Detalles Bibliográficos
Autores principales:	Kassimatis, Theodoros I, Giannopoulou, Ioanna, Koumoundourou, Dimitra, Theodorakopoulou, Emily, Varakis, Ioannis, Nakopoulou, Lydia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2006
Materias:	Epigenetic Review Series
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933079/ http://dx.doi.org/10.2755/jcmm010.004.05

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