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Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-β as major players and therapeutic targets

Hepatic fibrosis is a scarring process that is associated with an increased and altered deposition of extracellular matrix in liver. At the cellular and molecular level, this progressive process is mainly characterized by cellular activation of hepatic stellate cells and aberrant activity of transfo...

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Detalles Bibliográficos
Autores principales: Gressner, A M, Weiskirchen, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933103/
https://www.ncbi.nlm.nih.gov/pubmed/16563223
http://dx.doi.org/10.1111/j.1582-4934.2006.tb00292.x