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Dobesilate diminishes activation of the mitogen - activated protein kinase ERK1/2 in glioma cells

Fibroblast growth factors (FGFs) and their receptors, regularly expressed at high levels in gliomas, are further upregulated during the transition of the tumor from low- to high-grade malignancy, and are essential for glioma progression. FGFs induce upregulation of the mitogen-activated protein kina...

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Detalles Bibliográficos
Autores principales: Cuevas, P, Diaz-González, Diana, Garcia-Martin-Córdova, C, Sánchez, I, Lozano, Rosa Maria, Giménez-Gallego, G, Dujovny, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933114/
https://www.ncbi.nlm.nih.gov/pubmed/16563234
http://dx.doi.org/10.1111/j.1582-4934.2006.tb00303.x