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Losartan attenuates phospholipase C isozyme gene expression in hypertrophied hearts due to volume overload

Because the left ventricular (LV) hypertrophy due to volume overload induced by arteriovenous (AV) shunt was associated with an increase in phospholipase C (PLC) isozyme mRNA levels, PLC is considered to be involved in the development of cardiac hypertrophy. Since the renin-angiotensin system (RAS)...

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Detalles Bibliográficos
Autores principales: Dent, Melissa R, Aroutiounova, Nina, Dhalla, N S, Tappia, P S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933134/
https://www.ncbi.nlm.nih.gov/pubmed/16796812
http://dx.doi.org/10.1111/j.1582-4934.2006.tb00412.x