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Losartan attenuates phospholipase C isozyme gene expression in hypertrophied hearts due to volume overload
Because the left ventricular (LV) hypertrophy due to volume overload induced by arteriovenous (AV) shunt was associated with an increase in phospholipase C (PLC) isozyme mRNA levels, PLC is considered to be involved in the development of cardiac hypertrophy. Since the renin-angiotensin system (RAS)...
Autores principales: | Dent, Melissa R, Aroutiounova, Nina, Dhalla, N S, Tappia, P S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933134/ https://www.ncbi.nlm.nih.gov/pubmed/16796812 http://dx.doi.org/10.1111/j.1582-4934.2006.tb00412.x |
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