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Abnormal Expression Pattern of the IL-2 Receptor β-Chain on CD4(+) T Cells in ANCA-Associated Vasculitis
Background/Aim. ANCA-associated vasculitis (AAV) is a small-vessel vasculitis of autoimmune origin. In addition to autoantibodies, T cells have a pivotal pathophysiological role in this disease. T-cell homeostasis and immune tolerance critically depend on IL-2 and its receptor expressed by T cells....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933302/ https://www.ncbi.nlm.nih.gov/pubmed/24648606 http://dx.doi.org/10.1155/2014/249846 |