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Abnormal Expression Pattern of the IL-2 Receptor β-Chain on CD4(+) T Cells in ANCA-Associated Vasculitis

Background/Aim. ANCA-associated vasculitis (AAV) is a small-vessel vasculitis of autoimmune origin. In addition to autoantibodies, T cells have a pivotal pathophysiological role in this disease. T-cell homeostasis and immune tolerance critically depend on IL-2 and its receptor expressed by T cells....

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Detalles Bibliográficos
Autores principales: Wilde, Benjamin, Hoerning, André, Kribben, Andreas, Witzke, Oliver, Dolff, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933302/
https://www.ncbi.nlm.nih.gov/pubmed/24648606
http://dx.doi.org/10.1155/2014/249846

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