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Alanine-glyoxylate aminotransferase 2 (AGXT2) Polymorphisms Have Considerable Impact on Methylarginine and β-aminoisobutyrate Metabolism in Healthy Volunteers

Elevated plasma concentrations of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine have repeatedly been linked to adverse clinical outcomes. Both methylarginines are substrates of alanine-glyoxylate aminotransferase 2 (AGXT2). It was the aim of the present study to simultaneously investigate...

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Detalles Bibliográficos
Autores principales:	Kittel, Anja, Müller, Fabian, König, Jörg, Mieth, Maren, Sticht, Heinrich, Zolk, Oliver, Kralj, Ana, Heinrich, Markus R., Fromm, Martin F., Maas, Renke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933329/ https://www.ncbi.nlm.nih.gov/pubmed/24586340 http://dx.doi.org/10.1371/journal.pone.0088544

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