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Comprehensive Analysis of HPV16 Integration in OSCC Reveals No Significant Impact of Physical Status on Viral Oncogene and Virally Disrupted Human Gene Expression

Infection with high-risk human papillomavirus (HPV) type 16 is an independent risk factor for the development of oropharyngeal squamous cell carcinomas (OSCC). However, it is unclear whether viral integration is an essential hallmark in the carcinogenic process of OSCC and whether HPV integration co...

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Detalles Bibliográficos
Autores principales:	Olthof, Nadine C., Speel, Ernst-Jan M., Kolligs, Jutta, Haesevoets, Annick, Henfling, Mieke, Ramaekers, Frans C. S., Preuss, Simon F., Drebber, Uta, Wieland, Ulrike, Silling, Steffi, Lam, Wan L., Vucic, Emily A., Kremer, Bernd, Klussmann, Jens-P., Huebbers, Christian U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933331/ https://www.ncbi.nlm.nih.gov/pubmed/24586376 http://dx.doi.org/10.1371/journal.pone.0088718

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