A Unique Profile of Adenomatous Polyposis Coli Gene Mutations in Iranian Patients Suffering Sporadic Colorectal Cancer

OBJECTIVE: Colorectal cancer (CRC) is one of the most common and aggressive cancers worldwide. The majority of CRC cases are sporadic that caused by somatic mutations. The Adenomatous Polyposis Coli (APC; OMIM 611731) is a tumor suppressor gene of Wnt pathway and is frequently mutated in CRC cases....

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Detalles Bibliográficos
Autores principales: Hasanpour, Mojtaba, Galehdari, Hamid, Masjedizadeh, Abdolrahim, Ajami, Naser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933435/
https://www.ncbi.nlm.nih.gov/pubmed/24518971

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