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The VHL gene is epigenetically inactivated in pheochromocytomas and abdominal paragangliomas

Pheochromocytoma (PCC) and abdominal paraganglioma (PGL) are neuroendocrine tumors that present with clinical symptoms related to increased catecholamine levels. About a third of the cases are associated with constitutional mutations in pre-disposing genes, of which some may also be somatically muta...

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Detalles Bibliográficos
Autores principales: Andreasson, Adam, Kiss, Nimrod B, Caramuta, Stefano, Sulaiman, Luqman, Svahn, Fredrika, Bäckdahl, Martin, Höög, Anders, Juhlin, C Christofer, Larsson, Catharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933494/
https://www.ncbi.nlm.nih.gov/pubmed/24149047
http://dx.doi.org/10.4161/epi.26686