PIAS1 Regulates Breast Tumorigenesis through Selective Epigenetic Gene Silencing

Epigenetic gene silencing by histone modifications and DNA methylation is essential for cancer development. The molecular mechanism that promotes selective epigenetic changes during tumorigenesis is not understood. We report here that the PIAS1 SUMO ligase is involved in the progression of breast tu...

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Detalles Bibliográficos
Autores principales: Liu, Bin, Tahk, Samuel, Yee, Kathleen M., Yang, Randy, Yang, Yonghui, Mackie, Ryan, Hsu, Cary, Chernishof, Vasili, O'Brien, Neil, Jin, Yusheng, Fan, Guoping, Lane, Timothy F., Rao, Jianyu, Slamon, Dennis, Shuai, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933565/
https://www.ncbi.nlm.nih.gov/pubmed/24586797
http://dx.doi.org/10.1371/journal.pone.0089464

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