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Identification of Transforming Hepatitis B Virus S Gene Nonsense Mutations Derived from Freely Replicative Viruses in Hepatocellular Carcinoma

BACKGROUND & AIMS: The correlation between chronic hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) has been well-established. But the roles of viral factor remain uncertain. Only HBV X gene and nonsense mutations of S gene (C-terminal truncation of HBV surface protein) have...

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Detalles Bibliográficos
Autores principales: Huang, Shiu-Feng, Chen, Ya-Ting, Lee, Wei-Chen, Chang, Il-Chi, Chiu, Yu-Ting, Chang, Yu, Tu, Hsiao-Chen, Yuh, Chiou-Hwa, Matsuura, Isao, Shih, Liang-Yu, Lai, Ming-Wei, Wu, Hong-Dar Isaac, Chen, Miin-Fu, Yeh, Chau-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933656/
https://www.ncbi.nlm.nih.gov/pubmed/24587012
http://dx.doi.org/10.1371/journal.pone.0089753