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Structure and Biomechanics of the Endothelial Transcellular Circumferential Invasion Array in Tumor Invasion

Cancer cells breach the endothelium not only through cell-cell junctions but also via individual endothelial cells (ECs), or transcellular invasion. The underlying EC forms a circular structure around the transcellular invasion pore that is dependent on myosin light chain kinase (MLCK) and myosin II...

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Detalles Bibliográficos
Autores principales: Arvanitis, Constadina, Khuon, Satya, Spann, Rachel, Ridge, Karen M., Chew, Teng-Leong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933692/
https://www.ncbi.nlm.nih.gov/pubmed/24587014
http://dx.doi.org/10.1371/journal.pone.0089758