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Intranasal influenza vaccination using a new synthetic mucosal adjuvant SF‐10: induction of potent local and systemic immunity with balanced Th1 and Th2 responses

BACKGROUND: We found previously that bovine pulmonary Surfacten(®) used in newborns with acute respiratory distress syndrome is a safe and efficacious antigen vehicle for intranasal vaccination. OBJECTIVES: The objective of this study was to industrially produce a synthetic adjuvant mimicking Surfac...

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Detalles Bibliográficos
Autores principales: Kimoto, Takashi, Mizuno, Dai, Takei, Tsunetomo, Kunimi, Takuya, Ono, Shinji, Sakai, Satoko, Kido, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933764/
https://www.ncbi.nlm.nih.gov/pubmed/23710832
http://dx.doi.org/10.1111/irv.12124