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Alcohol modulation of G-protein-gated inwardly rectifying potassium channels: from binding to therapeutics
Alcohol (ethanol)-induced behaviors may arise from direct interaction of alcohol with discrete protein cavities within brain proteins. Recent structural and biochemical studies have provided new insights into the mechanism of alcohol-dependent activation of G protein-gated inwardly rectifying potass...
Autores principales: | Bodhinathan, Karthik, Slesinger, Paul A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933770/ https://www.ncbi.nlm.nih.gov/pubmed/24611054 http://dx.doi.org/10.3389/fphys.2014.00076 |
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