Cargando…

Dose Ramadan Fasting Affects Inflammatory Responses: Evidences for Modulatory Roles of This Unique Nutritional Status via Chemokine Network

Objective(s): The impact of fasting in Ramadan as a unique type of nutritional regimen on biochemical and hematological parameters is still an issue of debate. Almost very little is known regarding the regulatory role(s) of this nutritional status on immune responses or inflammation. Materials and M...

Descripción completa

Detalles Bibliográficos
Autores principales: Akrami Mohajeri, Fateme, Ahmadi, Zahra, Hassanshahi, Gholamhossein, Akrami Mohajeri, Elham, Ravari, Ali, Ghalebi, Seyed Razi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933797/
https://www.ncbi.nlm.nih.gov/pubmed/24570826
_version_ 1782304994582593536
author Akrami Mohajeri, Fateme
Ahmadi, Zahra
Hassanshahi, Gholamhossein
Akrami Mohajeri, Elham
Ravari, Ali
Ghalebi, Seyed Razi
author_facet Akrami Mohajeri, Fateme
Ahmadi, Zahra
Hassanshahi, Gholamhossein
Akrami Mohajeri, Elham
Ravari, Ali
Ghalebi, Seyed Razi
author_sort Akrami Mohajeri, Fateme
collection PubMed
description Objective(s): The impact of fasting in Ramadan as a unique type of nutritional regimen on biochemical and hematological parameters is still an issue of debate. Almost very little is known regarding the regulatory role(s) of this nutritional status on immune responses or inflammation. Materials and Methods: The levels of biochemical parameters were determined using commercial diagnostic kits. Hematological parameters were also examined. We also employed ELISA for detection of CXCL1, CXCL10 and CXCL12 chemokines. The Student-T test was used to compare the values of different parameters obtained in the first and last day of Ramadan fasting by employing SPSS (version 18) software. Results: As our findings demonstrated, there was a markedly difference between before and after Ramadan BMI of the individuals who fast. Our results also revealed that there was a remarkable difference between the levels of total cholesterol, FBS, Triglycerides and LDL before and after Ramadan fasting. Results revealed that among studied hematological parameters only the numbers of platelets were markedly different before and after Ramadan fasting program in individuals who practice fasting. Our results also showed decreased levels of pro-inflammatory CXC chemokines but unaltered levels of homoeostatic ones. Conclusion: The results of this study may reveal that Ramadan fasting is quite safe for normal healthy adults and so very useful in reduction of cholesterol and triglycerides in relation with dyslipidemia. It is also possible to conclude that fasting is important in controlling of inflammation via chemokines.
format Online
Article
Text
id pubmed-3933797
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Mashhad University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-39337972014-02-25 Dose Ramadan Fasting Affects Inflammatory Responses: Evidences for Modulatory Roles of This Unique Nutritional Status via Chemokine Network Akrami Mohajeri, Fateme Ahmadi, Zahra Hassanshahi, Gholamhossein Akrami Mohajeri, Elham Ravari, Ali Ghalebi, Seyed Razi Iran J Basic Med Sci Original Article Objective(s): The impact of fasting in Ramadan as a unique type of nutritional regimen on biochemical and hematological parameters is still an issue of debate. Almost very little is known regarding the regulatory role(s) of this nutritional status on immune responses or inflammation. Materials and Methods: The levels of biochemical parameters were determined using commercial diagnostic kits. Hematological parameters were also examined. We also employed ELISA for detection of CXCL1, CXCL10 and CXCL12 chemokines. The Student-T test was used to compare the values of different parameters obtained in the first and last day of Ramadan fasting by employing SPSS (version 18) software. Results: As our findings demonstrated, there was a markedly difference between before and after Ramadan BMI of the individuals who fast. Our results also revealed that there was a remarkable difference between the levels of total cholesterol, FBS, Triglycerides and LDL before and after Ramadan fasting. Results revealed that among studied hematological parameters only the numbers of platelets were markedly different before and after Ramadan fasting program in individuals who practice fasting. Our results also showed decreased levels of pro-inflammatory CXC chemokines but unaltered levels of homoeostatic ones. Conclusion: The results of this study may reveal that Ramadan fasting is quite safe for normal healthy adults and so very useful in reduction of cholesterol and triglycerides in relation with dyslipidemia. It is also possible to conclude that fasting is important in controlling of inflammation via chemokines. Mashhad University of Medical Sciences 2013-12 /pmc/articles/PMC3933797/ /pubmed/24570826 Text en © 2013: Iranian Journal of Basic Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Akrami Mohajeri, Fateme
Ahmadi, Zahra
Hassanshahi, Gholamhossein
Akrami Mohajeri, Elham
Ravari, Ali
Ghalebi, Seyed Razi
Dose Ramadan Fasting Affects Inflammatory Responses: Evidences for Modulatory Roles of This Unique Nutritional Status via Chemokine Network
title Dose Ramadan Fasting Affects Inflammatory Responses: Evidences for Modulatory Roles of This Unique Nutritional Status via Chemokine Network
title_full Dose Ramadan Fasting Affects Inflammatory Responses: Evidences for Modulatory Roles of This Unique Nutritional Status via Chemokine Network
title_fullStr Dose Ramadan Fasting Affects Inflammatory Responses: Evidences for Modulatory Roles of This Unique Nutritional Status via Chemokine Network
title_full_unstemmed Dose Ramadan Fasting Affects Inflammatory Responses: Evidences for Modulatory Roles of This Unique Nutritional Status via Chemokine Network
title_short Dose Ramadan Fasting Affects Inflammatory Responses: Evidences for Modulatory Roles of This Unique Nutritional Status via Chemokine Network
title_sort dose ramadan fasting affects inflammatory responses: evidences for modulatory roles of this unique nutritional status via chemokine network
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933797/
https://www.ncbi.nlm.nih.gov/pubmed/24570826
work_keys_str_mv AT akramimohajerifateme doseramadanfastingaffectsinflammatoryresponsesevidencesformodulatoryrolesofthisuniquenutritionalstatusviachemokinenetwork
AT ahmadizahra doseramadanfastingaffectsinflammatoryresponsesevidencesformodulatoryrolesofthisuniquenutritionalstatusviachemokinenetwork
AT hassanshahigholamhossein doseramadanfastingaffectsinflammatoryresponsesevidencesformodulatoryrolesofthisuniquenutritionalstatusviachemokinenetwork
AT akramimohajerielham doseramadanfastingaffectsinflammatoryresponsesevidencesformodulatoryrolesofthisuniquenutritionalstatusviachemokinenetwork
AT ravariali doseramadanfastingaffectsinflammatoryresponsesevidencesformodulatoryrolesofthisuniquenutritionalstatusviachemokinenetwork
AT ghalebiseyedrazi doseramadanfastingaffectsinflammatoryresponsesevidencesformodulatoryrolesofthisuniquenutritionalstatusviachemokinenetwork