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Determination of parameter identifiability in nonlinear biophysical models: A Bayesian approach

A major goal of biophysics is to understand the physical mechanisms of biological molecules and systems. Mechanistic models are evaluated based on their ability to explain carefully controlled experiments. By fitting models to data, biophysical parameters that cannot be measured directly can be esti...

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Detalles Bibliográficos
Autores principales: Hines, Keegan E., Middendorf, Thomas R., Aldrich, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933937/
https://www.ncbi.nlm.nih.gov/pubmed/24516188
http://dx.doi.org/10.1085/jgp.201311116