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Determination of parameter identifiability in nonlinear biophysical models: A Bayesian approach
A major goal of biophysics is to understand the physical mechanisms of biological molecules and systems. Mechanistic models are evaluated based on their ability to explain carefully controlled experiments. By fitting models to data, biophysical parameters that cannot be measured directly can be esti...
Autores principales: | Hines, Keegan E., Middendorf, Thomas R., Aldrich, Richard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933937/ https://www.ncbi.nlm.nih.gov/pubmed/24516188 http://dx.doi.org/10.1085/jgp.201311116 |
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