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Chronic Peripheral Administration of Kappa-Opioid Receptor Antagonist Advances Puberty Onset Associated with Acceleration of Pulsatile Luteinizing Hormone Secretion in Female Rats

Puberty in mammals is timed by an increase in gonadotropin-releasing hormone (GnRH) secretion. Previous studies have shown involvement of the two neuropeptides, kisspeptin and neurokinin B (NKB), in controlling puberty onset. Little is known about the role of the other key neuropeptide, dynorphin, i...

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Detalles Bibliográficos
Autores principales:	NAKAHARA, Tatsuo, UENOYAMA, Yoshihisa, IWASE, Akira, OISHI, Shinya, NAKAMURA, Sho, MINABE, Shiori, WATANABE, Youki, DEURA, Chikaya, NOGUCHI, Taro, FUJII, Nobutaka, KIKKAWA, Fumitaka, MAEDA, Kei-ichiro, TSUKAMURA, Hiroko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Society for Reproduction and Development 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934117/ https://www.ncbi.nlm.nih.gov/pubmed/23877505 http://dx.doi.org/10.1262/jrd.2013-046

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