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Nicotinamide: a Class III HDACi Delays In Vitro Aging of Mouse Oocytes

Postovulatory mammalian oocyte developmental potential decreases with aging in vivo and in vitro. Aging oocytes typically show cellular fragmentation and chromosome scattering with an abnormally shaped spindle over time. Previously, it was shown that histone acetylation in the mouse oocyte increased...

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Detalles Bibliográficos
Autores principales:	LEE, Ah Reum, KISHIGAMI, Satoshi, AMANO, Tomoko, MATSUMOTO, Kazuya, WAKAYAMA, Teruhiko, HOSOI, Yoshihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Society for Reproduction and Development 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934134/ https://www.ncbi.nlm.nih.gov/pubmed/23474603 http://dx.doi.org/10.1262/jrd.2012-171

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