Epiblast Cell Number and Primary Embryonic Stem Cell Colony Generation Are Increased by Culture of Cleavage Stage Embryos in Insulin

Human embryos for hESC derivation are often donated at the cleavage stage and of reduced quality. Poor quality embryos have lower efficiency for hESC derivation. However, cleavage stage mouse embryos develop into higher quality expanded blastocysts if they are cultured with insulin, suggesting that...

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Detalles Bibliográficos
Autores principales: CAMPBELL, Jared M., LANE, Michelle, VASSILIEV, Ivan, NOTTLE, Mark B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934205/
https://www.ncbi.nlm.nih.gov/pubmed/23171593
http://dx.doi.org/10.1262/jrd.2012-103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934205/
https://www.ncbi.nlm.nih.gov/pubmed/23171593
http://dx.doi.org/10.1262/jrd.2012-103

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