Spire and Formin 2 Synergize and Antagonize in Regulating Actin Assembly in Meiosis by a Ping-Pong Mechanism

In mammalian oocytes, three actin binding proteins, Formin 2 (Fmn2), Spire, and profilin, synergistically organize a dynamic cytoplasmic actin meshwork that mediates translocation of the spindle toward the cortex and is required for successful fertilization. Here we characterize Fmn2 and elucidate t...

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Detalles Bibliográficos
Autores principales: Montaville, Pierre, Jégou, Antoine, Pernier, Julien, Compper, Christel, Guichard, Bérengère, Mogessie, Binyam, Schuh, Melina, Romet-Lemonne, Guillaume, Carlier, Marie-France
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934834/
https://www.ncbi.nlm.nih.gov/pubmed/24586110
http://dx.doi.org/10.1371/journal.pbio.1001795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934834/
https://www.ncbi.nlm.nih.gov/pubmed/24586110
http://dx.doi.org/10.1371/journal.pbio.1001795

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