Normalization of RNA-Sequencing Data from Samples with Varying mRNA Levels

Methods for normalization of RNA-sequencing gene expression data commonly assume equal total expression between compared samples. In contrast, scenarios of global gene expression shifts are many and increasing. Here we compare the performance of three normalization methods when polyA(+) RNA content...

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Detalles Bibliográficos
Autores principales: Aanes, Håvard, Winata, Cecilia, Moen, Lars F., Østrup, Olga, Mathavan, Sinnakaruppan, Collas, Philippe, Rognes, Torbjørn, Aleström, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934880/
https://www.ncbi.nlm.nih.gov/pubmed/24586560
http://dx.doi.org/10.1371/journal.pone.0089158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934880/
https://www.ncbi.nlm.nih.gov/pubmed/24586560
http://dx.doi.org/10.1371/journal.pone.0089158

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