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Normalization of RNA-Sequencing Data from Samples with Varying mRNA Levels
Methods for normalization of RNA-sequencing gene expression data commonly assume equal total expression between compared samples. In contrast, scenarios of global gene expression shifts are many and increasing. Here we compare the performance of three normalization methods when polyA(+) RNA content...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934880/ https://www.ncbi.nlm.nih.gov/pubmed/24586560 http://dx.doi.org/10.1371/journal.pone.0089158 |