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Organic Cation Transporter-Mediated Ergothioneine Uptake in Mouse Neural Progenitor Cells Suppresses Proliferation and Promotes Differentiation into Neurons

The aim of the present study is to clarify the functional expression and physiological role in neural progenitor cells (NPCs) of carnitine/organic cation transporter OCTN1/SLC22A4, which accepts the naturally occurring food-derived antioxidant ergothioneine (ERGO) as a substrate in vivo. Real-time P...

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Detalles Bibliográficos
Autores principales: Ishimoto, Takahiro, Nakamichi, Noritaka, Hosotani, Hiroshi, Masuo, Yusuke, Sugiura, Tomoko, Kato, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934899/
https://www.ncbi.nlm.nih.gov/pubmed/24586778
http://dx.doi.org/10.1371/journal.pone.0089434