Cargando…

Sutherlandia frutescens Ethanol Extracts Inhibit Oxidative Stress and Inflammatory Responses in Neurons and Microglial Cells

Sutherlandia frutescens (L.) R.Br. (SF) is a medicinal plant indigenous to southern Africa and used in folk and contemporary remedies for stress, chronic diseases, cancer, and HIV/AIDS. While previous studies have focused on physiological effects of SF on cellular and systemic abnormalities associat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Jinghua, Chuang, Dennis Y., Zong, Yijia, Patel, Jayleenkumar, Brownstein, Korey, Lei, Wei, Lu, Chi-Hua, Simonyi, Agnes, Gu, Zezong, Cui, Jiankun, Rottinghaus, George E., Fritsche, Kevin L., Lubahn, Dennis B., Folk, William R., Sun, Grace Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934922/ https://www.ncbi.nlm.nih.gov/pubmed/24587007 http://dx.doi.org/10.1371/journal.pone.0089748

Ejemplares similares

An Investigation into the Immunomodulatory Activities of Sutherlandia frutescens in Healthy Mice
por: Lei, Wei, et al.
Publicado: (2016)

Dietary Sutherlandia and Elderberry Mitigate Cerebral Ischemia-Induced Neuronal Damage and Attenuate p47phox and Phospho-ERK1/2 Expression in Microglial Cells
por: Chuang, Dennis Y., et al.
Publicado: (2014)

Inhibition of Hedgehog-Signaling Driven Genes in Prostate Cancer Cells by Sutherlandia frutescens Extract
por: Lu, Yuan, et al.
Publicado: (2015)

Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells
por: Chuang, Dennis Y, et al.
Publicado: (2013)

Sutherlandia frutescens may exacerbate HIV-associated neuroinflammation
por: Africa, Luan Dane, et al.
Publicado: (2015)

Antioxidant potential of Sutherlandia frutescens and its protective effects against oxidative stress in various cell cultures
por: Tobwala, Shakila, et al.
Publicado: (2014)

Cytosolic phospholipase A(2) plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway
por: Chuang, Dennis Y., et al.
Publicado: (2015)

The mutagenic and antimutagenic activity of Sutherlandia frutescens extracts and marker compounds
por: Ntuli, Siyabulela S. B. N., et al.
Publicado: (2018)

The Induction of Apoptosis in A375 Malignant Melanoma Cells by Sutherlandia frutescens
por: van der Walt, Nicola B., et al.
Publicado: (2016)

Consumption of Sutherlandia frutescens by HIV-Seropositive South African Adults: An Adaptive Double-Blind Randomized Placebo Controlled Trial
por: Wilson, Douglas, et al.
Publicado: (2015)

Quercetin Attenuates Inflammatory Responses in BV-2 Microglial Cells: Role of MAPKs on the Nrf2 Pathway and Induction of Heme Oxygenase-1
por: Sun, Grace Y., et al.
Publicado: (2015)

Effect of the African Traditional Medicine, Sutherlandia frutescens, on the Bioavailability of the Antiretroviral Protease Inhibitor, Atazanavir
por: Müller, Adrienne C., et al.
Publicado: (2013)

Anticancer Potential of Sutherlandia frutescens and Xysmalobium undulatum in LS180 Colorectal Cancer Mini-Tumors
por: Gouws, Chrisna, et al.
Publicado: (2021)

Isolation of alpha-linolenic acid from Sutherlandia frutescens and its inhibition of Mycobacterium tuberculosis’ shikimate kinase enzyme
por: Masoko, Peter, et al.
Publicado: (2016)

The effect of Aspalathin linearis, Cyclopia intermedia and Sutherlandia frutescene on sperm functional parameters of healthy male wistar rats
por: Omolaoye, Temidayo S., et al.
Publicado: (2023)

Effects of aged garlic extract and FruArg on gene expression and signaling pathways in lipopolysaccharide-activated microglial cells
por: Song, Hailong, et al.
Publicado: (2016)

The Implication of Chemotypic Variation on the Anti-Oxidant and Anti-Cancer Activities of Sutherlandia frutescens (L.) R.Br. (Fabaceae) from Different Geographic Locations
por: Zonyane, Samkele, et al.
Publicado: (2020)

The Effect of Rooibos (Aspalathus linearis), Honeybush (Cyclopia intermedia) and Sutherlandia (Lessertia frutescens) on Testicular Insulin Signalling in Streptozotocin-Induced Diabetes in Wistar Rats
por: Omolaoye, Temidayo S, et al.
Publicado: (2021)

Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA(2)-IIA expression in astrocytes and microglia
por: Sheng, Wenwen, et al.
Publicado: (2011)

NitroDIGE analysis reveals inhibition of protein S-nitrosylation by epigallocatechin gallates in lipopolysaccharide-stimulated microglial cells
por: Qu, Zhe, et al.
Publicado: (2014)

Comparative cardio and developmental toxicity induced by the popular medicinal extract of Sutherlandia frutescens (L.) R.Br. detected using a zebrafish Tuebingen embryo model
por: Chen, Longsheng, et al.
Publicado: (2018)

Proteomic Analysis of the Effects of Aged Garlic Extract and Its FruArg Component on Lipopolysaccharide-Induced Neuroinflammatory Response in Microglial Cells
por: Zhou, Hui, et al.
Publicado: (2014)

Unveiling anti-oxidative and anti-inflammatory effects of docosahexaenoic acid and its lipid peroxidation product on lipopolysaccharide-stimulated BV-2 microglial cells
por: Yang, Bo, et al.
Publicado: (2018)

Quercetin Potentiates Docosahexaenoic Acid to Suppress Lipopolysaccharide-induced Oxidative/Inflammatory Responses, Alter Lipid Peroxidation Products, and Enhance the Adaptive Stress Pathways in BV-2 Microglial Cells
por: Sun, Grace Y., et al.
Publicado: (2019)

Prolonged exposure of cortical neurons to oligomeric amyloid-β impairs NMDA receptor function via NADPH oxidase-mediated ROS production: protective effect of green tea (–)-epigallocatechin-3-gallate
por: He, Yan, et al.
Publicado: (2011)

African herbal medicines in the treatment of HIV: Hypoxis and Sutherlandia. An overview of evidence and pharmacology
por: Mills, Edward, et al.
Publicado: (2005)

Proteomic Quantification and Site-Mapping of S-Nitrosylated Proteins Using Isobaric iodoTMT Reagents
por: Qu, Zhe, et al.
Publicado: (2014)

A Randomized, Double-Blind, Placebo-Controlled Trial of Lessertia frutescens in Healthy Adults
por: Johnson, Quinton, et al.
Publicado: (2007)

Two-Dimensional Zymography Differentiates Gelatinase Isoforms in Stimulated Microglial Cells and in Brain Tissues of Acute Brain Injuries
por: Chen, Shanyan, et al.
Publicado: (2015)

Bioactive components from garlic on brain resiliency against neuroinflammation and neurodegeneration
por: Song, Hailong, et al.
Publicado: (2020)

Perilla frutescens Leaf Extract Attenuates Vascular Dementia-Associated Memory Deficits, Neuronal Damages, and Microglial Activation
por: Kang, Hyun-Bae, et al.
Publicado: (2022)

Yin-Yang Mechanisms Regulating Lipid Peroxidation of Docosahexaenoic Acid and Arachidonic Acid in the Central Nervous System
por: Yang, Bo, et al.
Publicado: (2019)

Changes in the Harpagide, Harpagoside, and Verbascoside Content of Field Grown Scrophularia lanceolata and Scrophularia marilandica in Response to Season and Shade
por: Brownstein, Korey J., et al.
Publicado: (2021)

Comparative assessment on in vitro antioxidant activities of ethanol extracts of Averrhoa bilimbi, Gymnema sylvestre and Capsicum frutescens
por: Rahman, Md. Mominur, et al.
Publicado: (2014)

High accumulation of γ-linolenic acid and Stearidonic acid in transgenic Perilla (Perilla frutescens var. frutescens) seeds
por: Lee, Kyeong-Ryeol, et al.
Publicado: (2019)

Transcriptome analysis and identification of genes associated with ω-3 fatty acid biosynthesis in Perilla frutescens (L.) var. frutescens
por: Kim, Hyun Uk, et al.
Publicado: (2016)

Phytochemical study of polyphenols in Perilla Frutescens as an antioxidant
por: Asif, Mohammad
Publicado: (2012)

Evaluation of selected biological capacities of Baeckea frutescens
por: Navanesan, Suerialoasan, et al.
Publicado: (2015)

Applications of Perilla frutescens Extracts in Clinical Practice
por: Adam, Gigi, et al.
Publicado: (2023)

The Role and Mechanism of Perilla frutescens in Cancer Treatment
por: Huang, Shicong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kps1qlul56n6h4au0oa4kols4q